Effects of estradiol on cognition evaluated with P300 in in vitro fertilization patients
INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.114, sa.12, ss.1591-1599, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 114 Sayı: 12
- Basım Tarihi: 2004
- Doi Numarası: 10.1080/00207450490509357
- Dergi Adı: INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1591-1599
- Anahtar Kelimeler: cognition, estradiol, event related potentials, in-vitro fertilization, ESTROGEN REPLACEMENT THERAPY, SELECTIVE-ATTENTION, POTENTIALS
- Akdeniz Üniversitesi Adresli: Evet
Özet
The authors planned to show the effect of high-level estrogen on cognitive functions, using P300 in the in-vitro fertilization (IVF) population. Eighteen IVF patients (mean age 31.39+/-5.01) without any detectable cognitive disorder were enrolled in this study. The authors measured N100, P200, N200, P300 latencies and amplitudes at C-z and F-z recordings during the lowest and highest blood estradiol levels. P300 amplitudes were significantly reduced during the highest level of estradiol compared to the lowest level both at F and C, recordings. The other subcomponents of P300 were not significantly influenced by blood estradiol levels. The results revealed a decline in the ability of task relevance and state of arousal when the estradiol level was the highest in the IVF patients.