Effect of Cold Application and Tizanidine on Clonus: Clinical and Electrophysiological Assessment

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BOYRAZ I., Oktay F., CELIK C., AKYUZ M., Uysal H.

JOURNAL OF SPINAL CORD MEDICINE, vol.32, no.2, pp.132-139, 2009 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1080/10790268.2009.11760764
  • Journal Name: JOURNAL OF SPINAL CORD MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.132-139
  • Keywords: Spinal cord injuries, Spasticity, Clonus, Tizanidine, Tetraplegia, Hemiplegia, Cryotherapy, SPINAL-CORD-INJURY, MULTIPLE-SCLEROSIS, MUSCLE-SPINDLE, SPASTIC SUBJECTS, DOUBLE-BLIND, STRETCH, BACLOFEN, TRIAL
  • Open Archive Collection: AVESIS Open Access Collection
  • Akdeniz University Affiliated: Yes

Abstract

Background/Objectives: Clonus is an involuntary rhythmic muscle contraction after sudden muscle stretch that occurs as a result of a lesion in the upper motor neurons. The real mechanism behind clonus remains obscure. The objective of this study was to investigate the effects of central-acting tizanidine treatment and peripheral extremity cooling on clonus.