ATYPICAL MRI FINDINGS IN CEREBRAL ADRENOLEUKODY STROPHY: A CASE REPORT

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Koc K., Canan A., Koc P., KARAALİ K., DUMAN Ö., Senol U.

ACTA CLINICA CROATICA, cilt.60, sa.2, ss.326-328, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.20471/acc.2021.60.02.23
  • Dergi Adı: ACTA CLINICA CROATICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.326-328
  • Anahtar Kelimeler: Adrenoleukodystrophy, Magnetic resonance imaging, Very-long-chain fatty acids, White matter, X-LINKED ADRENOLEUKODYSTROPHY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation of very-long-chain fatty acids in all body tissues, thus causing demyelination of the white matter. Magnetic resonance imaging (MRI) is a reliable radiological modality to demonstrate the extension of brain lesions and severity of the disease. In the classic form, the parieto-occipital white matter is affected. Besides, atypical MRI findings such as primary frontal lobe involvement are rarely described. We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral symmetric frontal lobe white matter changes suggesting anterior predominance.