Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

ÖZSOY Ö., ÖZSOY U., Stein G., Semler O., Skouras E., Schempf G., ...Daha Fazla

RESTORATIVE NEUROLOGY AND NEUROSCIENCE, cilt.30, sa.5, ss.363-381, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 5
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3233/rnn-2012-110203
  • Dergi Adı: RESTORATIVE NEUROLOGY AND NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.363-381
  • Anahtar Kelimeler: Compression spinal cord injury, injury severity, bladder function, BBB rating scale, urinary bladder innervation, LOWER URINARY-TRACT, EXTERNAL URETHRAL SPHINCTER, BOTULINUM-TOXIN-A, PONTINE MICTURITION CENTER, NERVE GROWTH-FACTOR, RAT BLADDER, ULTRASTRUCTURAL EVIDENCE, INTRAVESICAL CAPSAICIN, AUTONOMIC DYSREFLEXIA, PERIAQUEDUCTAL GRAY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Following spinal cord injury (SCI), loss of spinal and supraspinal control results in desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter (sympathicus) activity. Despite recovery of lower urinary tract function being a high priority in patients with SCI, effective treatment options are unavailable largely because mechanisms are poorly understood.