Good response to HBsAg vaccine in dialysis patients is associated with high CD4+/CD8+ ratio


Sari F., TAŞKAPAN H.

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.44, no.5, pp.1501-1506, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 5
  • Publication Date: 2012
  • Doi Number: 10.1007/s11255-011-0043-6
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1501-1506
  • Keywords: Chronic renal failure, Hepatitis B vaccination, Candida skin test, CD4+, CD8+, HEPATITIS-B-VACCINE, T-CELL, IMMUNE-RESPONSES, HEMODIALYSIS, INFECTION, ANERGY, TUBERCULIN
  • Akdeniz University Affiliated: Yes

Abstract

Chronic renal failure is accompanied by various abnormalities of innate and acquired, cellular and humoral immunity. We aimed to investigate whether positive Candida skin test results, CD4+ and CD8+, before the first dose of vaccination could be a predictor for antibody response to hepatitis B vaccination and the relation of these parameters with hepatitis B antibody levels 1 month after the last dose of vaccination.