Skin Reactions Developing After Anti-Tumor Necrosis Factor Treatment: A Paradoxical Side Effect

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Kutluk O., Umal Enginar A., BALCI N., BÜTÜN B., KAÇAR C.

ARCHIVES OF RHEUMATOLOGY, cilt.34, sa.1, ss.100-104, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5606/archrheumatol.2019.6882
  • Dergi Adı: ARCHIVES OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.100-104
  • Anahtar Kelimeler: Anti-tumor necrosis factor treatment, paradoxical side effect, psoriasis, FACTOR ANTAGONIST THERAPY, NEW-ONSET PSORIASIS, ALPHA
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The use of anti-tumor necrosis factor (anti-TNF) therapies for treatment of rheumatic diseases is increasing every day and the results are positive. Case reports about skin reactions developing after use of these medications - newly developing psoriasis, increase/flare-up of existing psoriasis - are found in the literature at rates that cannot be ignored. Psoriasis developing after the use of these agents for treatment is a paradoxical side effect, with no clear understanding of the cause though several hypotheses exist. In this article, we present five cases with this paradoxical side effect developing after anti-TNF treatment accompanied by the literature with the aim of aiding in finding an approach to these cases.