The importance of serum intestinal fatty acid-binding protein for the early diagnosis of acute mesenteric ischemia


Zenger S., Piroglu I. D., Cevik A., Ozcabi Y., Fakioglu D., Senol M., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.27, no.3, pp.278-283, 2021 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.14744/tjtes.2020.35823
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.278-283
  • Keywords: Acute mesenteric ischemia, biomarker, early diagnosis, intestinal fatty acid-binding protein, I-FABP, PLASMA BIOMARKERS, CELIAC-DISEASE, D-LACTATE, MORTALITY, MARKER, DAMAGE, LEVEL
  • Akdeniz University Affiliated: Yes

Abstract

BACKGROUND: Acute mesenteric ischemia (AMI), although relatively rare, is an emergency condition with high mortality rates (60-80%) attributed to lack of early diagnosis. The aim of this experimental study was to observe the changes in serum intestinal fatty acid-binding protein (I-FABP) levels over time in the AMI model by ligating superior mesenteric artery (SMA) in rats and to compare with the serum I-FABP levels of the rats in the control group.