The importance of serum intestinal fatty acid-binding protein for the early diagnosis of acute mesenteric ischemia


Zenger S., Piroglu I. D., Cevik A., Ozcabi Y., Fakioglu D., Senol M., ...Daha Fazla

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.27, sa.3, ss.278-283, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.14744/tjtes.2020.35823
  • Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.278-283
  • Anahtar Kelimeler: Acute mesenteric ischemia, biomarker, early diagnosis, intestinal fatty acid-binding protein, I-FABP, PLASMA BIOMARKERS, CELIAC-DISEASE, D-LACTATE, MORTALITY, MARKER, DAMAGE, LEVEL
  • Akdeniz Üniversitesi Adresli: Evet

Özet

BACKGROUND: Acute mesenteric ischemia (AMI), although relatively rare, is an emergency condition with high mortality rates (60-80%) attributed to lack of early diagnosis. The aim of this experimental study was to observe the changes in serum intestinal fatty acid-binding protein (I-FABP) levels over time in the AMI model by ligating superior mesenteric artery (SMA) in rats and to compare with the serum I-FABP levels of the rats in the control group.