Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea

Ozdem S. S., SADAN G., USTA C., TASATARGIL A.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.27, sa.4, ss.299-305, 2000 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1046/j.1440-1681.2000.03231.x
  • Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.299-305
  • Anahtar Kelimeler: baclofen, diabetes, GABA, GABA(B) receptors, rat trachea, GAMMA-AMINOBUTYRIC-ACID, BRONCHIAL SMOOTH-MUSCLE, GUINEA-PIG TRACHEA, MUSCARINIC RECEPTORS, ACETYLCHOLINE-RELEASE, B INHIBITION, STREPTOZOTOCIN, MODULATION, NEURONS, INVITRO
  • Akdeniz Üniversitesi Adresli: Evet

Özet

1. In the present study, we investigated the effect of GABA and selective GABA agonists and antagonists on neurally induced tracheal contractions in streptozotocin (STZ) diabetic rats.