Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea


Ozdem S. S., SADAN G., USTA C., TASATARGIL A.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.27, no.4, pp.299-305, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2000
  • Doi Number: 10.1046/j.1440-1681.2000.03231.x
  • Journal Name: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.299-305
  • Keywords: baclofen, diabetes, GABA, GABA(B) receptors, rat trachea, GAMMA-AMINOBUTYRIC-ACID, BRONCHIAL SMOOTH-MUSCLE, GUINEA-PIG TRACHEA, MUSCARINIC RECEPTORS, ACETYLCHOLINE-RELEASE, B INHIBITION, STREPTOZOTOCIN, MODULATION, NEURONS, INVITRO
  • Akdeniz University Affiliated: Yes

Abstract

1. In the present study, we investigated the effect of GABA and selective GABA agonists and antagonists on neurally induced tracheal contractions in streptozotocin (STZ) diabetic rats.