Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea

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Ozdem S. S., SADAN G., USTA C., TASATARGIL A.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.27, no.4, pp.299-305, 2000 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 27 Issue: 4
• Publication Date: 2000
• Doi Number: 10.1046/j.1440-1681.2000.03231.x
• Journal Name: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.299-305
• Keywords: baclofen, diabetes, GABA, GABA(B) receptors, rat trachea, GAMMA-AMINOBUTYRIC-ACID, BRONCHIAL SMOOTH-MUSCLE, GUINEA-PIG TRACHEA, MUSCARINIC RECEPTORS, ACETYLCHOLINE-RELEASE, B INHIBITION, STREPTOZOTOCIN, MODULATION, NEURONS, INVITRO
• Akdeniz University Affiliated: Yes

Abstract

1. In the present study, we investigated the effect of GABA and selective GABA agonists and antagonists on neurally induced tracheal contractions in streptozotocin (STZ) diabetic rats.