Novel transmitters in brain stem vagal neurocircuitry: new players on the pitch

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BÜLBÜL M., Travagli R. A.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, cilt.315, sa.1, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 315 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1152/ajpgi.00059.2018
  • Dergi Adı: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: apelin, nesfatin, neuropeptide S, stomach, stress, NEUROPEPTIDE-S RECEPTOR, PITUITARY-ADRENAL AXIS, DORSAL MOTOR NUCLEUS, INHIBITS GASTRIC-MOTILITY, DISTAL COLONIC TRANSIT, NERVOUS-SYSTEM CONTROL, PARAVENTRICULAR NUCLEUS, APJ RECEPTOR, OPIOID RECEPTORS, CENTRAL APELIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The last few decades have seen a major increase in the number of neurotransmitters and neuropeptides recognized as playing a role in brain stem neurocircuits, including those involved in homeostatic functions such as stress responsiveness, gastrointestinal motility, feeding, and/or arousal/wakefulness. This minireview will focus on the known physiological role of three of these novel neuropeptides, i.e., apelin, nesfatin-1, and neuropeptide-S, with a special emphasis on their hypothetical roles in vagal signaling related to gastrointestinal motor functions.