Prognostic significance of biological apoptosis factors in gastric cancer


Sezer C., Yildirim M., Yildiz M., Sezgin A., Dilli U. D., Goktas S., ...More

JOURNAL OF BUON, vol.18, no.1, pp.138-146, 2013 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2013
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.138-146
  • Keywords: apoptosis, bcl-2, gastric cancer, p53, P53 PROTEIN EXPRESSION, BCL-2 EXPRESSION, CLINICOPATHOLOGICAL FACTORS, CELL-PROLIFERATION, ACCUMULATION, CARCINOMAS, MARKERS, SURVIVAL, KI-67
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Gastric cancer is a biologically heterogeneous disease containing many genetic and epigenetic alterations. In our study, the expression status of apoptosis-inducing p53 and apoptosis-inhibiting Bcl-2 in gastric cancer and their relation with prognosis, if any, was investigated.