Assessment of Citrullinated Myelin by H-1-MR Spectroscopy in Early-Onset Multiple Sclerosis

Oguz, K.; Kurne, A.; Aksu, A.; KARABULUT, ERDEM; Serdaroglu, A.; Teber, S.; Haspolat, ŞENAY; Senbil, N.; Kurul, S.; Anlar, B.

doi:10.3174/ajnr.a1425

Assessment of Citrullinated Myelin by H-1-MR Spectroscopy in Early-Onset Multiple Sclerosis

Oguz K. K., Kurne A., Aksu A. O., KARABULUT E., Serdaroglu A., Teber S., ...More

AMERICAN JOURNAL OF NEURORADIOLOGY, vol.30, no.4, pp.716-721, 2009 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 30 Issue: 4
Publication Date: 2009
Doi Number: 10.3174/ajnr.a1425
Journal Name: AMERICAN JOURNAL OF NEURORADIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.716-721
Open Archive Collection: AVESIS Open Access Collection
Akdeniz University Affiliated: Yes

Abstract

BACKGROUND AND PURPOSE: Myelin instability and citrullinated myelin basic protein have been demonstrated in the brains of patients with chronic and fulminating forms of multiple sclerosis (MS). Our aim was to trace citrulline in the brains of patients with early-onset MS by using proton MR spectroscopy (H-1-MR spectroscopy).