Is Retinal Nerve Fiber Layer Thickness Change Related to Headache Lateralization in Migraine?


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Gunes A., Demirci S., TÖK L., TÖK Ö., DEMİRCİ S., KUTLUHAN S.

Korean journal of ophthalmology : KJO, cilt.30, sa.2, ss.134-139, 2016 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3341/kjo.2016.30.2.134
  • Dergi Adı: Korean journal of ophthalmology : KJO
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.134-139
  • Anahtar Kelimeler: Migraine, Retinal nerve fiber layer thickness, Unilateral headache
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

PURPOSE: To evaluate retinal nerve fiber layer (RNFL) thickness in migraine patients with unilateral headache.METHODS: A total of 58 patients diagnosed with migraine headache consistently occurring on the same side and 58 age- and sex-matched healthy subjects were evaluated in this cross-sectional study. RNFL thickness was measured using spectral-domain optical coherence tomography, and the side with the headache was compared with the contralateral side as well as with the results of healthy subjects.RESULTS: The mean patient age was 33.05 ± 8.83 years, and that of the healthy subjects was 31.44 ± 8.64 years (p = 0.32). The mean duration of disease was 10.29 ± 9.03 years. The average and nasal RNFL thicknesses were significantly thinner on the side of headache and on the contralateral side compared to control eyes (p < 0.05, for all). Thinning was higher on the side of the headache compared to the contralateral side; however, this difference was not statistically significant.CONCLUSIONS: The RNFL thicknesses were thinner on the side of the headache compared to the contralateral side in the migraine patients with unilateral headache, but this difference was not statistically significant.