Critical time point for apoptotic cell death in an experimental ischemia/reperfusion model and the effect of N-acetylcystein

ÖZŞARLAK SÖZER G., EMRE M., Demirkol S., AÇIKALIN A., ÇETİNER S., TOPÇU Z., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.42, sa.3, ss.265-272, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1515/tjb-2016-0306
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.265-272
  • Anahtar Kelimeler: Kidney, Transplantation, Ischemia/reperfusion, Apoptosis, N-acetylcystein, ISCHEMIA-REPERFUSION INJURY, ACUTE KIDNEY INJURY, ACUTE-RENAL-FAILURE, OXIDATIVE STRESS, RAT-KIDNEY, TRANSPLANTATION, ACID, PATHOPHYSIOLOGY, PRETREATMENT, ATTENUATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Kidney transplantation is an important treatment option in end stage renal failure. Tissue death may be an important problem when a kidney is removed from a cadaver and transported to a donor a long distance away. The purpose of this study is to determine the critical time point for apoptotic cell death in a renal ischemia/reperfusion model and determine the effects of N-acetylcystein on apoptosis induced by ischemia injury.