A macrophage activation marker chitotriosidase in women with PCOS: does low-grade chronic inflammation in PCOS relate to PCOS itself or obesity?

Alanbay I., Ercan C. M., SAKINCI M., Coksuer H., Ozturk M., Tapan S.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.286, sa.4, ss.1065-1071, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 286 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00404-012-2425-0
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1065-1071
  • Anahtar Kelimeler: Chitotriosidase, Inflammation, Macrophage, PCOS, POLYCYSTIC-OVARY-SYNDROME, INSULIN-RESISTANCE, ADIPOSE-TISSUE, FAT DISTRIBUTION, ADIPOCYTE DEATH, EXPRESSION, GLUCOSE, EXCESS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Polycystic ovary syndrome (PCOS) is described as a low-grade chronic inflammatory state where the macrophage infiltration increased in visceral fat play the major role. The aim of this study was to assess chitotriosidase (ChT) activity (an activated macrophage marker) in women with PCOS and controls and to evaluate its correlation with anthropometric and biochemical parameters.