Could Topical Minoxidil Cause Non-Arteritic Anterior Ischemic Optic Neuropathy?

Aktas H., Alan S., Türkoglu E. B., Sevik Ö.

Journal of clinical and diagnostic research : JCDR, cilt.10, 2016 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Teknik Not
  • Cilt numarası: 10
  • Basım Tarihi: 2016
  • Doi Numarası: 10.7860/jcdr/2016/19679.8250
  • Dergi Adı: Journal of clinical and diagnostic research : JCDR
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
  • Anahtar Kelimeler: Androgeneticalopecia, Eye, Optic nerve, NAION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Minoxidil hair formulation is commonly used for the treatment of male or female androgenic alopecia. Minoxidil is a Health Canada and US FDA-approved medication for hair loss in men and women. The drug is marketed as 2% and 5% topical solutions. This over-thecounter product is considered safe, but should be used with caution. Furthermore, minoxidil is an orally active vasodilator for treatment of severe hypertension. Typical side effects of minoxidil are faster heart rate, augmented heart function and stroke volume (which can be associated with reduced vascular resistance upon baroflex stimulus), retained sodium and water and abnormal hair growth. The most common adverse reactions of the topical formulation are limited to irritant and allergic contact dermatitis on the scalp. Herein, we report a non-arteritic anterior ischemic optic neuropathy caused by topical 5% minoxidil treatment that was resolved after discontinuation of minoxidil.