Damage induced by paracetamol compared with N-acetylcysteine

Kisaoglu A., Ozogul B., TURAN M. I., Yilmaz I., Demiryilmaz I., ATAMANALP S. S., ...More

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, vol.77, no.9, pp.463-468, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 77 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jcma.2014.01.011
  • Journal Name: JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.463-468
  • Keywords: hepatotoxicity, paracetamol, rat, thiamine, thiamine pyrophosphate, ACETAMINOPHEN-INDUCED HEPATOTOXICITY, SUPEROXIDE-DISMUTASE, NITRIC-OXIDE, THIAMINE PYROPHOSPHATE, GLUTATHIONE-PEROXIDASE, OXIDATIVE STRESS, FREE-RADICALS, ANTIOXIDANTS, CATALASE, TISSUES
  • Akdeniz University Affiliated: No

Abstract

Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol.