Research Information System
International Conference for Multiple Academic Disciplines Zurich - Switzerland (ICMAD17Swiss Conference), Zürich, Switzerland, 7 - 09 July 2017, pp.743, (Summary Text)
Herbal Theraphies Used in Type 2 Diabetes Mellitus: Systematic Review
Abstract
Nature is a miracle source of medicine of anti-diabetes. Recently more than 1200 flowers are admitted to have anti-diabetes peculiarities. In the treatment of type 2 diabetes mellitus (T2DM), the use of complementary therapies has increased recently. The aim of this systematic review is to analyze randomized control group studies on herbal therapies which individuals used as complementary in addition to medicine.
This systematic review consists of studies done between 2000 and 2016. Systematic review was based on key words of “Type 2 diabetes mellitus, herbal products and randomized controlled trial” in January in 2017. In the studies full articles reached from Science citation index (43), Directory of open access journals (16), Academic one file (15), Scobus (10), Social sciences citation index (7), Cinahl Complete (10), Medline (5), Science Direct (5), Academic search complete (3), General one file (2), Google academic (10) were systematically reviewed. In this study, following research questions were sought to answer: Which herbal therapies do individuals with T2DM use mostly? What are the herbal therapies determined to be effective? What are the effects of used herbal therapies on blood glucose and blood lipids? When were the individuals using herbal therapies diagnosed with T2DM?
According to the results of the study, it was seen that individuals with T2DM used mostly the herbal products such as “cinnamon, agaricus blazei murrill mushroom, xiaoke pill (traditional china medicine), green tea, hibiscus sabdariffa (sour tea), resveretrol, vernonia cinerea, fructus mume formüle (traditional china medicine), satureja khuzestanica, goshajinkian, silybum marianum, broccoli sprouts powder, rauvolfia-citrus (traditional nigerian medicine), salacia reticulata (kothala himbutu tea), pancreas tonic (an ayurvedic herbal supplement), syzjium cummuni skeels (java plum), prunium110 (bittter oranges and mulbery leaves), TM81 (tang-min-ling-wan), green tea and sour tea, ginger, Chinese herbal medicine jinlida, cinnamon and Caucasian whortleberry”. When the effects of those herbal products in individuals with T2DM on their fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c) and blood lipids were analyzed, in the studies done with eleven herbal products (cinnamon, resveretrol, silybum marianum, salacia reticulata, vernonia cinerea, goshajinkigan, rauvolfia-citrus tea, pancreas tonic (an ayurvedic herbal supplement), Chinese herbal medicine jinlida and TM81 (tang-min-ling-wan), ginger) it was found that there was a significant decrease in FBG ve HbA1c different from placebo groups. Although six herbal products (fructus mume formule, green tea, PURIAM110 (bitter oranges ve mulberry leaves), green tea ve sour tea, cinnamon and Caucasian whortleberry) were seen to cause a decrease in FBG and HbA1c, this was seen as insignificant when compared to placebo groups. However in the seven studies systematically reviewed, seven herbal products (cinnamon, silybum marianum, green tea, sour tea, satureja khuzestanica, vernonia cinerea, broccoli shrouds powder) were found to cause a significant decrease in blood lipids effectively. The diagnosis periods of individuals with T2DM using herbal products were observed as five or few years.
The evidence supporting the effectiveness of herbal products as a treatment choice for T2DM are insufficient. It was determined that more studies to prove the effectiveness of herbal products are necessary. In order to support the safety of individuals with T2DM using herbal products, health professionals should interact with them effectively and be aware of effects and side effects of herbal products.
Key Words: Complementary medicine, Type 2 diabetes mellitus, randomized control trials