The predictive role of Bcl-2 expression in operable locally advanced or metastatic gastric carcinoma

Yildirim M., Suren D., Goktas S., Dilli U. D., Kaya C., Copuroglu R., ...Daha Fazla

JOURNAL OF BUON, cilt.17, sa.1, ss.106-109, 2012 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2012
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.106-109
  • Anahtar Kelimeler: Bcl-2, chemotherapy, gastric cancer, prediction of response, PROGNOSTIC-SIGNIFICANCE, FAMILY-MEMBERS, P53 EXPRESSION, CANCER, APOPTOSIS, PROTEIN, PLUS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Gastric carcinoma is an aggressive disease with different epidemiologic and clinical profiles. Combination chemotherapy containing docetaxel, cisplatin and 5-fluorouracil/5-FU (DCF) is a frequently used regimen in metastatic gastric cancer We studied the role of B-cell lymphoma 2 (Bcl-2) expression in predicting the response to DCF combination chemotherapy in metastatic gastric carcinoma.