The predictive role of Bcl-2 expression in operable locally advanced or metastatic gastric carcinoma
JOURNAL OF BUON, vol.17, no.1, pp.106-109, 2012 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 17 Issue: 1
- Publication Date: 2012
- Journal Name: JOURNAL OF BUON
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.106-109
- Keywords: Bcl-2, chemotherapy, gastric cancer, prediction of response, PROGNOSTIC-SIGNIFICANCE, FAMILY-MEMBERS, P53 EXPRESSION, CANCER, APOPTOSIS, PROTEIN, PLUS
- Akdeniz University Affiliated: Yes
Abstract
Purpose: Gastric carcinoma is an aggressive disease with different epidemiologic and clinical profiles. Combination chemotherapy containing docetaxel, cisplatin and 5-fluorouracil/5-FU (DCF) is a frequently used regimen in metastatic gastric cancer We studied the role of B-cell lymphoma 2 (Bcl-2) expression in predicting the response to DCF combination chemotherapy in metastatic gastric carcinoma.