The predictive role of Bcl-2 expression in operable locally advanced or metastatic gastric carcinoma
JOURNAL OF BUON, cilt.17, sa.1, ss.106-109, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 1
- Basım Tarihi: 2012
- Dergi Adı: JOURNAL OF BUON
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.106-109
- Anahtar Kelimeler: Bcl-2, chemotherapy, gastric cancer, prediction of response, PROGNOSTIC-SIGNIFICANCE, FAMILY-MEMBERS, P53 EXPRESSION, CANCER, APOPTOSIS, PROTEIN, PLUS
- Akdeniz Üniversitesi Adresli: Evet
Özet
Purpose: Gastric carcinoma is an aggressive disease with different epidemiologic and clinical profiles. Combination chemotherapy containing docetaxel, cisplatin and 5-fluorouracil/5-FU (DCF) is a frequently used regimen in metastatic gastric cancer We studied the role of B-cell lymphoma 2 (Bcl-2) expression in predicting the response to DCF combination chemotherapy in metastatic gastric carcinoma.