Continuous Erythropoietin Receptor Activator Ameliorates Diabetic Kidney Disease in Rats

Gunal M. Y., Eren Z., Bakir E. A.

TURKISH JOURNAL OF NEPHROLOGY, cilt.29, sa.4, ss.264-272, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/turkjnephrol.2020.3958
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.264-272
  • Anahtar Kelimeler: Continuous erythropoietin receptor activator, diabetic kidney disease, inflammation, oxidative stress, experimental model, renin-angiotensin system, OXIDATIVE STRESS, EPOETIN BETA, NEPHROPATHY, PATHWAYS, ISCHEMIA, MODEL, CERA
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Diabetic kidney disease (DKD) is still a significant cause of morbidity in patients with diabetes. In this study, we examined the potential effects of continuous erythropoietin receptor activator (CERA) on oxidative stress, inflammation, and the renin-angiotensin system in a rat model of DKD induced by streptozocin.