Correlation between intrahepatic hepatitis B virus cccDNA levels and other activity markers in patients with HBeAg-negative chronic hepatitis B infection

GUNER, Rahmet; Karahocagil, Mustafa; Buyukberber, Mehmet; Kandemir, Ozlem; Ural, Onur; USLUER, GAYE; İNAN, DİLARA; Koksal, Iftihar; BAYKAM, Nurcan; Hizel, Kenan; Yamazhan, Tansu; Esen, Saban; TASYARAN, Mehmet

doi:10.1097/meg.0b013e32834ba13a

Correlation between intrahepatic hepatitis B virus cccDNA levels and other activity markers in patients with HBeAg-negative chronic hepatitis B infection

Atıf İçin Kopyala

GUNER R., Karahocagil M., Buyukberber M., Kandemir O., Ural O., USLUER G., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.23, sa.12, ss.1185-1191, 2011 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 12
Basım Tarihi: 2011
Doi Numarası: 10.1097/meg.0b013e32834ba13a
Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1185-1191
Anahtar Kelimeler: hepatitis B core antigen, hepatitis B early antigen-negative chronic hepatitis, hepatitis B surface antigen, hepatitis B virus, hepatitis B virus covalently closed circular DNA, immunohistochemistry, quantitative hepatitis B surface antigen, HBV DNA LEVELS, CLOSED CIRCULAR DNA, SURFACE-ANTIGEN, NATURAL-HISTORY, LIVER HISTOLOGY, HBSAG LEVELS, CORE, THERAPY, DECLINE, REPLICATION
Akdeniz Üniversitesi Adresli: Evet

Özet

Objective The aim of this study was to demonstrate the relation between intrahepatic (IH) hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) levels and the other HBV replicative intermediates and hepatocyte expression of HBV antigens.