Atıf İçin Kopyala
Sözen B., Ozekinci M., ERMAN M., GUNDUZ T., DEMİR N., AKOURI R.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, cilt.36, sa.10, ss.2181-2189, 2019 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
36
Sayı:
10
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Basım Tarihi:
2019
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Doi Numarası:
10.1007/s10815-019-01560-4
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Dergi Adı:
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.2181-2189
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Anahtar Kelimeler:
Rat, Galactosemia, Primary ovarian insufficiency, DHEA, FOLLICLE-STIMULATING-HORMONE, GROWTH-FACTOR-I, ANDROGEN RECEPTOR, FAILURE, EXPRESSION, WOMEN, OOCYTE, ACTIVATION, NUMBER, MICE
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Akdeniz Üniversitesi Adresli:
Evet
Özet
Purpose Almost every female classic galactosemia patient develops primary ovarian insufficiency (POI). The unique pathophysiology of classic galactosemia, with a severely reduced follicle pool at an early age, requires a new therapeutic approach. This study evaluated the effect of dehydroepiandrosterone (DHEA) on ovarian tissue in a galactose-induced POI rat model.