Inflammation: an important parameter in the search of prostate cancer biomarkers

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Bergamini S., Bellei E., BONETTI L. R., Monari E., CUOGHI A., BORELLI F., ...More

PROTEOME SCIENCE, vol.12, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12
  • Publication Date: 2014
  • Doi Number: 10.1186/1477-5956-12-32
  • Journal Name: PROTEOME SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Inflammation, Prostate cancer biomarkers, Proteomics, SELDI ToF MS, 2 DE, PROTEOMIC ANALYSIS, ANTI-THROMBIN, PROTEIN, BENIGN, HYPERPLASIA, PROFILES, PROGRESSION, EXPRESSION, HEMOPEXIN, DISCOVERY
  • Open Archive Collection: AVESIS Open Access Collection
  • Akdeniz University Affiliated: Yes

Abstract

Background: A more specific and early diagnostics for prostate cancer (PCa) is highly desirable. In this study, being inflammation the focus of our effort, serum protein profiles were analyzed in order to investigate if this parameter could interfere with the search of discriminating proteins between PCa and benign prostatic hyperplasia (BPH).