Confirmation of anti-DFS70 antibodies is needed in routine clinical samples with DFS staining pattern

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MUTLU E., EYİGÖR M., MUTLU D., Gultekin M.

CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, vol.41, no.1, pp.6-11, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5114/ceji.2016.58812
  • Journal Name: CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.6-11
  • Keywords: DFS70, indirect immunofluorescence, line immunoassay, systemic autoimmune rheumatic disease, ANTINUCLEAR ANTIBODIES, HEALTHY-INDIVIDUALS, HEP-2 CELLS, AUTOANTIBODIES, LEDGF, IMMUNOFLUORESCENCE, ARTICLE, P75
  • Akdeniz University Affiliated: Yes

Abstract

Background: Recognition of nuclear dense fine speckled (DFS) pattern by indirect immunofluorescence (IIF) is not easy. Thus, confirming the presence of these antibodies might be needed. In this study, we aimed to determine the frequency of DFS pattern in our diagnostic laboratory and to investigate the presence of anti-DFS70 antibodies in samples showing DFS pattern by two commercially available research kits retrospectively.