Akademik Veri Yönetim Sistemi
Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology, cilt.31, sa.2, ss.68-76, 2022 (ESCI)
This study aimed to analyze the depressive and anxiety states of adolescent girls
with polycystic ovary syndrome (PCOS). This was a cross-sectional, multicenter, case–
control study. A total of 100 participants (PCOS group, 51; control group, 49) aged 13–18
years were included in the study. Body mass index was higher in patients with PCOS (P =
0.002). In the PCOS group, 28.5% of the patients had moderate-to-severe depressive
symptoms, whereas the incidence was lower in controls (8.3%, P = 0.021). The State-Trait
Anxiety Inventory (STAI)-State, STAI-Trait, and physical, psychosocial, and total Pediatric
Quality of Life Inventory PedsQL scores were higher in the PCOS group, suggesting that
anxiety was more common and the quality of life was worse in patients with PCOS than in
healthy participants (P = 0.01, P = 0.03, P = 0.02, P = 0.046, and P = 0.047, respectively). The
serum free testosterone (fT) levels were positively correlated with the depression and anxiety
scores and negatively correlated with the psychosocial PedsQL scores. In conclusion,
adolescent girls diagnosed with PCOS demonstrated higher depressive and anxiety symptoms
and lower psychosocial quality of life scores than their healthy counterparts. A relationship
was found between the fT level and all psychological measures