Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand.

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Sarı F., Yalçın A. D., Genç G. E., Sarıkaya M., Bisgin A., Çetinkaya R., ...Daha Fazla

Balkan medical journal, cilt.33, ss.512-516, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/balkanmedj.2016.150685
  • Dergi Adı: Balkan medical journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.512-516
  • Anahtar Kelimeler: Serum-soluble TNF-related apoptosis-inducing ligand, chronic kidney disease, autosomal dominant polycystic kidney disease, KIDNEY-DISEASE, DECOY RECEPTOR, CELL-SURVIVAL, TRAIL, DEATH, OSTEOPROTEGERIN, PROLIFERATION, INDUCTION, FAMILY, MEMBER
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple, large renal cysts and impaired kidney function. Although the reason for the development of kidney cysts is unknown, ADPKD is associated with cell cycle arrest and abundant apoptosis of renal tubular epithelial cells.