N-acetylcysteine fails to prevent renal dysfunction and oxidative stress after noniodine contrast media administration during percutaneous coronary interventions

Buyukhatipoglu, Hakan; Sezen, Yusuf; Yildiz, Ali; Bas, Memduh; KIRHAN, Idris; Ulas, TURGAY; TURAN, Mehmet; Taskin, Abdullah; Aksoy, Nurten

doi:10.20452/pamw.975

N-acetylcysteine fails to prevent renal dysfunction and oxidative stress after noniodine contrast media administration during percutaneous coronary interventions

Buyukhatipoglu H., Sezen Y., Yildiz A., Bas M., KIRHAN I., Ulas T., ...More

POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE, vol.120, no.10, pp.383-389, 2010 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 120 Issue: 10
Publication Date: 2010
Doi Number: 10.20452/pamw.975
Journal Name: POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.383-389
Keywords: N-acetylcysteine, contrast nephropathy, oxidative stress, total antioxidant capacity, total oxidant capacity, RANDOMIZED CONTROLLED-TRIAL, INDUCED NEPHROPATHY, OXIDANT STRESS, FREE-RADICALS, OSMOLAR, DAMAGE
Open Archive Collection: AVESIS Open Access Collection
Akdeniz University Affiliated: No

Abstract

INTRODUCTION Oxidative stress is believed to have a role in contrast-induced nephropathy. Based on this assumption, several known antioxidants have been studied to assess their effect on nephropathy, especially N-acetylcysteine (NAC). However, its usefulness has yet to be confirmed.