Akademik Veri Yönetim Sistemi
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.16, sa.5, ss.1913-1917, 2015 (Scopus)
Abstract
Background: Oesophageal squamous cell carcinoma (ESCC) is endemic in the Eastern Anatolian region of
Turkey. The present study was performed to identify risk factors for ESCC that specifically reflect the demography
and nutritional habits of individuals living in this region. Materials and Methods: The following parameters were
compared in 208 ESCC patients and 200 control individuals in the Eastern Anatolian region: age, sex, place of
living, socioeconomic level, education level, smoking, alcohol intake, nutritional habits, and food preservation
methods. Results: The mean age of ESCC patients was 56.2 years, and 87 (41.8%) were 65 years-old or older.
The ratio of women to men in the patient group was 1.39/1. ESCC patients consumed significantly less fruit and
yellow or green vegetables and more hot black tea, ‘boiled yellow butter’, and mouldy cheese than did control
individuals. Residence in rural areas, smoking, and cooking food by burning animal manure were also significantly
associated with ESCC. Conclusions: The consumption of boiled yellow butter and mouldy cheese, which are
specific to the Eastern Anatolian region, and the use of animal manure for food preparation were identified as
risk factors in this region. Further studies are required to potentially identify the carcinogenic substances that
promote the development of ESCC in this region.
Keywords: Oesophageal squamous cell carcinoma - Turkey - Eastern Anatolia - risk factors