Topical granulocyte colony-stimulating factor for the treatment of oral and genital ulcers of patients with Behcet's disease

Bacanli, A.; Dicle, ÖZLEM; Parmaksizoglu, B.; Yilmaz, ERTAN; Alpsoy, ERKAN

doi:10.1111/j.1468-3083.2006.01677.x

Topical granulocyte colony-stimulating factor for the treatment of oral and genital ulcers of patients with Behcet's disease

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Bacanli A., Dicle O. Y., Parmaksizoglu B., Yilmaz E., Alpsoy E.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, vol.20, no.8, pp.931-935, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 20 Issue: 8
Publication Date: 2006
Doi Number: 10.1111/j.1468-3083.2006.01677.x
Journal Name: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.931-935
Keywords: Behcet's disease, G-CSF, genital ulcers, oral ulcers, therapy, topical, IN-VITRO, CYTOKINE DRESSINGS, RHGM-CSF
Akdeniz University Affiliated: Yes

Abstract

Background Recurrent and painful ulcers of the oral mucosa and genital skin/mucosa are the most commonly observed manifestations in patients with Behcet's disease (BD). They affect patients' quality of life. Because of the effectiveness of granulocyte colony-stimulating factor (G-CSF) in wound healing, it may also be useful for the treatment of oral ulcers (OU) and genital ulcers (GU) of BD.