Nevus comedonicus syndrome: a case associated with multiple basal cell carcinomas and a rudimentary toe

Alpsoy E., Durusoy C., Ozbilim G., Karpuzoglu G., Yilmaz E.

INTERNATIONAL JOURNAL OF DERMATOLOGY, vol.44, no.6, pp.499-501, 2005 (SCI-Expanded) identifier identifier identifier


A 28-year-old man presented to our clinic for the evaluation of widespread black spots and cysts, in which recurrent infections could not be controlled by topical and systemic antimicrobials. He was first noted at birth to have a rudimentary toe on the right foot. By the age of 8 years, he had developed pitting on the neck and sole, many of which contained black dots. Over subsequent years, pigmented papules representing pigmented basal cell carcinomas (BCCs) also began to appear on the neck and chest. The patient gave a history of recurrent abscesses and cysts developing on the lesions after the age of 14 years. His personal history was negative for epileptiform attacks and congenital cataract. There was no parental consanguinity and no family history of any similar skin condition.