Plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels in G-6-PD-deficient and normal male children


Sarikcioglu S., Gumuslu S., Uysal N. E., Aksu T.

BIOLOGICAL TRACE ELEMENT RESEARCH, vol.99, no.1-3, pp.41-47, 2004 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 1-3
  • Publication Date: 2004
  • Doi Number: 10.1385/bter:99:1-3:041
  • Journal Name: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.41-47
  • Keywords: G-6-PD deficiency, plasma, erythrocyte, magnesium, manganese, zinc, calcium, OXIDATIVE STRESS, G6PD DEFICIENCY
  • Akdeniz University Affiliated: Yes

Abstract

Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose, we studied two groups consisting of 10 male children who are G-6-PD-deficient and 12 age-matched normal male children to compare plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels between G-6-PD-deficient and normal children. All assays were performed under normal conditions free of any oxidative attack that may result in hemolytic crisis in G-6-PD-deficient subjects. All parameters in each group did not differ significantly except for erythrocyte G-6-PD activities. These data show that plasma and erythrocyte trace element contents of G-6-PD-deficient subjects do not differ in normal conditions.