Antioxidant activities of Sideritis congesta Davis et Huber-Morath and Sideritis arguta Boiss et Heldr: Identification of free flavonoids and cinnamic acid derivatives

ERKAN N., ÇETİN H., Ayranci E.

FOOD RESEARCH INTERNATIONAL, vol.44, no.1, pp.297-303, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.foodres.2010.10.016
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.297-303
  • Keywords: Antioxidant activity, Cinnamic acid derivatives, Flavonoids, Sideritis arguta, Sideritis congesta, DITERPENOIDS, PHENOLS, TEA
  • Akdeniz University Affiliated: Yes


Different solvent extracts of endemic Sideritis (Labiatae) species, Sideritis congesta Davis et Huber-Morath and Sideritis arguta Boiss et Heldr, were analyzed for free flavonoids (quercetin, apigenin, myricetin and kaempferol) and cinnamic acid derivatives (rosmarinic acid, ferulic acid, caffeic acid, p-coumaric acid and chlorogenic acid) using HPLC-DAD. All the phenolics were quantified in acid-hydrolyzed extracts, except rosmarinic acid, chlorogenic acid and myricetin which were quantified in raw samples. Antioxidant activities of extracts of these two plants and many of their components in pure form were evaluated based on DPPH center dot and ABTS(center dot+) assays. In general, S. arguta extracts displayed higher antioxidant activity than S. congesta extracts possibly due to their richness in antioxidant components of strong activity. Acetone extract of S. arguta, with its strikingly high TEAC value of 3.2 mM trolox and low IC50 value of 38.3 mu g/mL showed the highest antioxidant potency among all extracts. alpha-tocopherol, the positive control, displayed IC50 and TEAC values of 33.8 mu g/mL and 2.9 mM trolox, respectively. No direct correlation was found between antioxidant activities and total phenolic contents of the plant extracts studied. (C) 2010 Elsevier Ltd. All rights reserved.