Use of a Y-Tube Conduit After Facial Nerve Injury Reduces Collateral Axonal Branching at the Lesion Site But Neither Reduces Polyinnervation of Motor Endplates Nor Improves Functional Recovery

HİZAY A., ÖZSOY U., DEMİREL B. M., ÖZSOY Ö., Angelova S. K., Ankerne J., ...Daha Fazla

NEUROSURGERY, cilt.70, sa.6, ss.1544-1556, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1227/neu.0b013e318249f16f
  • Dergi Adı: NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1544-1556
  • Anahtar Kelimeler: Entubulation, Facial nerve, Functional recovery, Motor neuron, Nerve repair, MANUAL STIMULATION, SELECTIVE REINNERVATION, SCIATIC-NERVE, RECONSTRUCTIVE SURGERY, MUSCLE REINNERVATION, TISSUE-SPECIFICITY, VIBRISSAL MOVEMENT, SKELETAL-MUSCLE, FEMORAL NERVE, SCHWANN-CELLS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

BACKGROUND: Despite increased understanding of peripheral nerve regeneration, functional recovery after surgical repair remains disappointing. A major contributing factor is the extensive collateral branching at the lesion site, which leads to inaccurate axonal navigation and aberrant reinnervation of targets.