Chromosome Abnormalities Identified in 457 Spontaneous Abortions and Their Histopathological Findings


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Yakut S., TORU H. S., Cetin Z., ÖZEL ERKAN D., ŞİMŞEK M., Mendilcioglu I., ...More

TURKISH JOURNAL OF PATHOLOGY, vol.31, no.2, pp.111-118, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.5146/tjpath.2015.01303
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.111-118
  • Keywords: Chromosomal abnormalities, Cytogenetic abnormalities, Pathology, Spontaneous abortion, INTERSTITIAL DELETION, MATERNAL AGE, PRENATAL-DIAGNOSIS, DOWNS-SYNDROME, TRISOMY-21, TRANSLOCATION, ASSOCIATION, NEWBORN, 7Q
  • Akdeniz University Affiliated: Yes

Abstract

Objective: About 15% of clinically recognized pregnancies result in spontaneous abortion in the first trimester and the vast majority of these are the result of chromosome abnormalities. Studies of chromosomal constitutions of first trimester spontaneous abortions have revealed that at least 50% of the abortions have an abnormal karyotype. In this study we aimed to report the single centre experience of anomalies detected in spontaneous abortions.