The Study describes the potential use of pomegranate peel extract as antioxidant in fish oil. The effects of pomegranate (Punica granatum) peel extract (PPE) of three different concentrations (100, 500 and 1.000 ppm) and synthetic antioxidant butylated hydroxytoluene (BHT), on the lipid oxidation of fish oil were compared. Formation of primary and secondary oxidation products in anchovy (Engraulis encrasicholus) oil in an elevated temperature (60 A degrees C) storage trial was examined by conducting peroxide value, UV spectrum, thiobarbituric acid and para-anisidine analyses. The results showed that the two (500 and 1.000 ppm) concentrations of PPE were more effective in retarding of lipid oxidation in fish oil, in which a dose-response relationship was observed. The antioxidant capacity of 500 ppm of PPE was with that of 100 ppm of BHT, but still weaker than that of 1.000 ppm of PPE. Anchovy oil pomegranate peel extract, byproduct of pomegranate juice fabric, exhibited favorable antioxidant effects and is preferable for effectively avoiding lipid oxidation in fish oil.