The Evaluation of the Performance of C. Diff Quik Chek Complete and Toxin A plus B (Clostridium difficile) DUO Diagnostic Tests Compared with Toxigenic Culture in the Diagnosis of Clostridium difficile Infection

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Yazısız H., Ozyurt O. K., Öngüt G., Baysan B. O., Dönmez L., Gunseren F., ...Daha Fazla

CLINICAL LABORATORY, cilt.66, sa.4, ss.537-540, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.7754/clin.lab.2019.190713
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.537-540
  • Anahtar Kelimeler: Clostridium difficile infection, Clostridium difficile toxin A, Clostridium difficile toxin B, glutamate dehydrogenase, toxigenic culture, GLUTAMATE-DEHYDROGENASE, ENZYME-IMMUNOASSAY, ASSAYS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Clostridium difficile is an important cause of nosocomial diarrhea and the best standard laboratory method for the diagnosis of C. difficile infection is controversial. In this study, we aimed to investigate the performance of Toxin A + B (Clostridium difficile) DUO kit which detects C difficile toxin A and B by the immunochromatographic method and C. Diff Quik Chek Complete (QCC) rapid membrane immunoassay kit which determines the presence of glutamate dehydrogenase (GDH) and C. difficile toxin A and B in stool samples, compared with toxigenic culture in the diagnosis of C. difficile infection.