Akademik Veri Yönetim Sistemi
7th Edition of Advanced Materials Science World Congress, London, İngiltere, 24 - 25 Mart 2025, ss.1
Viscoelastic properties of soft materials are
extensively explored using single- and multi-frequency Atomic Force Microscopy
(AFM) methods in liquids. Performing In-fluid AFM operations enables to acquire
higher observable sensitivity to properties of soft samples. Amplitude, phase
shift, and frequency shift sensitivity to varying properties of soft materials
can be gathered considering the effect of viscous loads in different AFM
operation modes. Significant improvements in the extraction of functional heterogeneity
of the biological materials can be achieved by conducting multi-parametric AFM
experiments. Obtaining ultra high-resolution images of uncoated DNA, DNA
molecules can easily interact with the tip of the micro-cantilever in liquid
mediums. Imaging DNA in liquids is much more desirable owing to the lower
imaging forces in viscous mediums. Highly sensitive analysis can also be
conducted for characterization of biomolecules and cells at the sub-nanometer
scale. Ultrastable AFMs providing subpiconewton force precision lead to
enhancements in AFM imaging techniques for new biological applications. In
addition to that, pairwise friction coefficients of polystyrene particles can
be measured in Newtonian liquids. Based on AFM measurements, the friction properties
of the particles can be related to macroscopic rheological behaviors. An
in-fluid AFM technique can also be regarded as an active micro-rheology method
in the investigation of the structures and dynamics of soft samples. The
micro-rheological methods bring significant improvements, especially in the
characterization of polymers and biological samples. Simultaneous imaging can
also be conducted to extract properties of the polymer-blend films in
high-speed AFM. Therefore, fluidic AFM techniques can be robustly utilized to
characterize soft materials with high selectivity and sensitivity for different
technological applications.