Systemic toxicity of tacrolimus given by various routes and the response to dose reduction


Akar Y., Yucel G., Durukan A., Yucel M., Arici G.

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol.33, no.1, pp.53-59, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1442-9071.2005.00942.x
  • Journal Name: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.53-59
  • Keywords: administration route, dose reduction, systemic toxicity, tacrolimus, CYCLOSPORINE-A, RENAL-FUNCTION, FK-506, FK506, KIDNEY, TRANSPLANTATION, HYPERLIPIDEMIA, NEPHROTOXICITY, METABOLISM, GLUCOSE
  • Akdeniz University Affiliated: No

Abstract

Purpose: To evaluate the long-term systemic toxicity of tacrolimus (FK-506) administered by various routes, and to assess the effect of dose reduction on toxicity.