Effect of cold-restraint stress on the distribution of trace elements in rat tissues

Izgut-Uysal V. N., Derin N., Agac A.

BIOLOGICAL TRACE ELEMENT RESEARCH, cilt.78, sa.1-3, ss.149-155, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 1-3
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1385/bter:78:1-3:149
  • Dergi Adı: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.149-155
  • Anahtar Kelimeler: zinc, copper, magnesium, manganese, stress, cold-restraint stress, OXIDATIVE STRESS, ZINC, METALLOTHIONEIN, BRAIN, INDUCTION, CADMIUM, METABOLISM, LIVER
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The aim of this study was to assess the effects of cold-restraint stress on blood and the other tissue levels of trace elements. The experiment was performed on male Swiss albino rats. The animals were divided to two groups: control and stressed groups. In the stressed group, the rats were subjected to immobilization for 4 h at 4 degreesC. At the end of the experimental period, blood and tissue samples were collected from all of the animals. The levels of zinc, copper, magnesium, and manganese were measured using flame and graphite furnace atomic absorption spectrometry. In rats subjected to stress, the zinc levels of serum were increased, whereas in the duodenum and brain, zinc was found to decrease when compared to the control. The magnesium content of both the stomach and duodenum were reduced, but the manganese levels of the liver, kidneys, and brain significantly increased because of stress. In conclusion, cold-restraint stress may affect the metabolic process by changing the distributions of zinc, magnesium, and manganese in tissues.