There might be a role for CD200 in the pathogenesis of autoimmune and inflammatory skin disorders


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Akman-Karakas A., Yalcin A. D., Koc S., GÜMÜŞLÜ S., Senol Y. Y., Ozkesici B., ...More

MEDICAL SCIENCE MONITOR, vol.19, pp.888-891, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19
  • Publication Date: 2013
  • Doi Number: 10.12659/msm.889624
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.888-891
  • Keywords: autoimmune, inflammatory, skin, soluble CD200 (sCD200), psoriasis, pemphigus, SCD200, OMALIZUMAB, EXPRESSION, IL-1-BETA, PSORIASIS, DELIVERY
  • Akdeniz University Affiliated: Yes

Abstract

Background: Soluble CD200 (sCD200) is a novel immuno-effective molecule, which acts to regulate inflammatory and acquired immune responses. Recently, our study group showed that sCD200 was present in serum and blister fluid in a patient with bullous pemphigoid and a patient with toxic epidermal necrolysis. We therefore planned this study to evaluate the sCD200 levels of autoimmune and inflammatory skin disorder patients and to compare them with that of healthy controls.