Temporal and spatial distribution of the aquaporin 1 in spinal cord and dorsal root ganglia after traumatic injuries of the sciatic nerve

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Kaya Y., ÖZSOY U., DEMİR N., HİZAY A., Suzen L. B., Angelov D. N., ...Daha Fazla

CHILDS NERVOUS SYSTEM, cilt.30, sa.10, ss.1679-1686, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 10
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00381-014-2472-x
  • Dergi Adı: CHILDS NERVOUS SYSTEM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1679-1686
  • Anahtar Kelimeler: Aquaporin 1, Spinal cord, Dorsal root ganglia, Sciatic nerve injury, WATER TRANSPORT, EXPRESSION, CHANNELS, MICE, TARGETS, LESSONS, BRAIN, CELLS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The aquaporin family comprises a large family of integral membrane proteins that enable the movement of water and other small, neutral solutes across plasma membranes. Although function and mechanism of aquaporins in central nervous system injury have been reported, the pathophysiologic role of aquaporin 1 (AQP1) in peripheral nerve has not been extensively documented. In the present study, we aimed to study the temporal and spatial distribution of AQP1 in spinal cord and dorsal root ganglia after sciatic nerve injury.