Melatonin and its therapeutic actions on peripheral nerve regeneration

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Kandemir Y. B., SARIKCIOĞLU L.

FOLIA MORPHOLOGICA, cilt.74, sa.3, ss.283-289, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 74 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5603/fm.2015.0043
  • Dergi Adı: FOLIA MORPHOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.283-289
  • Anahtar Kelimeler: melatonin, peripheral nerve, traumatic injuries, neuroma formation, RAT SCIATIC-NERVE, SCHWANN-CELL PROLIFERATION, FREE-RADICAL SCAVENGER, IN-VIVO, TRANSFORMING GROWTH-FACTOR-BETA-1, ISCHEMIA/REPERFUSION INJURY, REPERFUSION INJURY, OXIDATIVE DAMAGE, ARTERY-OCCLUSION, ELECTRON-DONOR
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Melatonin has many different roles in the human body, including its importance in circadian rhythms, sleep physiology, mental status, reproduction, tumour development, ageing, and many other physiologic processes. Although there are more than hundreds of studies on effects of melatonin in several tissues, its effects on peripheral nerve has been documented in a limited number of studies. This paper focused to review the available literature in terms of several actions and effects of melatonin (beneficial or toxic effects) on well-known peripheral nerve injury models.