Topical Application of Tacrolimus Prevents Epidural Fibrosis in a Rat Postlaminectomy Model: Histopathological and Ultrastructural Analysis

İSMAİLOĞLU Ö., Albayrak B., Gulsen I., TANRIÖVER G., DEMİR N.

TURKISH NEUROSURGERY, cilt.21, sa.4, ss.630-633, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5137/1019-5149.jtn.4954-11.1
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.630-633
  • Anahtar Kelimeler: Epidural fibrosis, Laminectomy, Tacrolimus, Rat, LAMINECTOMY SCAR FORMATION, SDZ ASM 981, ANTIINFLAMMATORY DRUG, MITOMYCIN-C, PERIDURAL FIBROSIS, SKIN DISEASES, PHARMACOLOGY, INHIBITION, SURGERY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

AIM: Postlaminectomy epidural fibrosis is the formation of scar tissue over the dura mater following posterior spinal surgery. This devastating complication is responsible for the substantial amount of failed back syndromes.