Levels of plasma fibrinogen and D-dimer in subjects with subclinical hyperthyroidism
MEDICAL SCIENCE MONITOR, vol.14, no.1, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 1
- Publication Date: 2008
- Journal Name: MEDICAL SCIENCE MONITOR
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: cardiovascular risk, fibrinogen, D-dimer, subclinic hyperthyroidism, ISCHEMIC-HEART-DISEASE, LOW SERUM THYROTROPIN, THYROID-DISEASE, MYOCARDIAL-INFARCTION, FIBRINOLYTIC-ACTIVITY, HEMOSTATIC FUNCTION, BLOOD-COAGULATION, RISK-FACTOR, EPIDEMIOLOGY, ACTIVATION
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Background: During the last 15 years, several risk markers for atherosclerosis, such as fibrinogen and D-dimer; have been identified. The role of elevated fibrinogen levels as an independent risk factor for coronary, cerebral, and peripheral vascular disease is well established on the basis of clinical and epidemiological studies. Increased D-dimer levels are associated with increased risk of future myocardial infarction, stroke, and peripheral vascular disease. The aim of this study was to evaluate the alterations in fibrinogen and D-dimer, which indicates overall thrombotic activity, in subjects with subclinical hyperthyroidism.