The effect of sulfur dioxide inhalation on active avoidance learning, antioxidant status and lipid peroxidation during aging


Yargicoglu P., Sahin E., Gumuslu S., Agar A.

NEUROTOXICOLOGY AND TERATOLOGY, vol.29, no.2, pp.211-218, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1016/j.ntt.2006.11.002
  • Journal Name: NEUROTOXICOLOGY AND TERATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.211-218
  • Keywords: active avoidance, SO2, aging, antioxidant system, lipid peroxidation, pat, AGE-RELATED ALTERATIONS, SUPEROXIDE-DISMUTASE, GLUTATHIONE-PEROXIDASE, OXIDATIVE DAMAGE, POTASSIUM CURRENTS, HYDROGEN-PEROXIDE, EVOKED POTENTIALS, RAT-BRAIN, VITAMIN-E, ENZYMES
  • Akdeniz University Affiliated: Yes

Abstract

The effect of SO2 was examined on active avoidance learning, thiobarbituric acid reactive substances (TBARS), and the activities of Cu, Zn superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) in young (3 months), middle-age (12 months), and old (24 months) Swiss male albino rats. Ten ppm SO2 Was administered to the animals of SO2 groups in an exposure chamber for 1 h/day x 7 days/week x 6 weeks while control groups were exposed to filtered air in the same condition.