Effects of Carboxin on Glutathione-S-Transferase Enzyme Activite in Rainbow Trout (Oncorhynchus mykiss)

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AYDIN A., ALAK G., KOCAMAN E. M., ATAMANALP M.

JOURNAL OF ANIMAL AND VETERINARY ADVANCES, vol.11, no.15, pp.2716-2720, 2012 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 15
  • Publication Date: 2012
  • Doi Number: 10.3923/javaa.2012.2716.2720
  • Journal Name: JOURNAL OF ANIMAL AND VETERINARY ADVANCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2716-2720
  • Keywords: Carboxin, rainbow trout, toxicity, antioxidant enzyme, GST, MDA, OXIDATIVE STRESS RESPONSES, FRESH-WATER FISH, ANTIOXIDANT ENZYMES, LIPID-PEROXIDATION, TILAPIA, BIOMARKERS, TISSUE, LIVER, EXPOSURE, CATALASE
  • Open Archive Collection: AVESIS Open Access Collection
  • Akdeniz University Affiliated: Yes

Abstract

Carboxin is one of the most widely used fungicides in agriculture but information about toxicity on fish is limited. The aim of this study was to determine the effects of exposure to carboxin on the Antioxidant Defense System of rainbow trout (Oncorhynchus mykiss). The fish were exposed to carboxin (3.85 ppm) for 7 days. The antioxidant parameter (Glutathione-S-Transferase (GST)) was measured in fish liver samples. The results indicated that carboxin exposure significantly affected the activity of GST in rainbow trout liver (p < 0.05). Thus, it was assumed that carboxin caused oxidative stress in rainbow trout and GST enzyme played a role in protection against carboxin toxicity.