Infantile spasms: Knowledge, attitude, and practice of pediatricians in Turkey

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Yılmaz D., Yayıcı Köken Ö., Gürkaş E., Ceylan N., Çıtak Kurt A. N.

Epilepsy and Behavior, vol.126, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 126
  • Publication Date: 2022
  • Doi Number: 10.1016/j.yebeh.2021.108456
  • Journal Name: Epilepsy and Behavior
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE, Psycinfo
  • Keywords: Infantile spasms syndrome, KAP study, Turkish pediatricians
  • Akdeniz University Affiliated: Yes


Background: Infantile Spasms Syndrome (ISS) encompasses both West syndrome (WS), comprising epileptic spasms, psychomotor stagnation or regression and hypsarrhythmia, and also infants presenting with epileptic spasms who do not fulfill the triad of WS. Objective: To investigate the knowledge, attitude, and practice regarding ISS among Turkish pediatricians and pediatric residents. Methods: A cross-sectional study was conducted among pediatricians and pediatric residents from all regions of Turkey. Knowledge, attitude, and practice (KAP) about ISS were assessed using a questionnaire including 45 questions. Results: Out of 174 participants, 91.4% of respondents thought that ISS was a type of epilepsy. The two most recognized etiologic causes were structural abnormalities (90.8%) and genetic disorders (90.2%). Infantile colic (78.7%) and gastroesophageal reflux (75.9%) were reported to be the most common confusing diagnoses in this study. Almost all the respondents agreed that EEG recordings should be obtained for a patient with suspected ISS. Half of the participants stated that steroids were the first choice for treatment. Nearly all participants agreed on referring a pediatric patient with suspected ISS to a pediatric neurologist. Conclusion: Our findings highlight the importance of medical education as awareness is critical for diagnosing ISS. To facilitate rapid diagnosis, it is also important to combine medical education with public action. To ensure a sufficient level of knowledge about epileptic spasms and ISS, a strategy based on the socio-cultural characteristics of each population should be developed.