Effects of SNPS on the Secondary Protein Structure of Leptin Receptor Gene in the Long Term Selected Japanese Quails


KARABAĞ K., alkan s., KARSLI T.

27th International Scientific-Expert Congress of Agriculture and Food Industry, Bursa, Turkey, 26 - 28 September 2016, pp.120

  • Publication Type: Conference Paper / Full Text
  • City: Bursa
  • Country: Turkey
  • Page Numbers: pp.120
  • Akdeniz University Affiliated: Yes

Abstract

In this study, 5 SNP loci were detected in 350 bp DNA fragment of leptin receptor gene coding sequences from total 30 individuals belong to three genotypes (C, HBW and LBW) which were selected through 15 generations in terms of live weight. All detected SNP loci were examined individually and possible amino acid sequences and secondary protein structures were revealed. There were shown that as first and third SNPs located at the end of the codon which did not change the proline amino acid corresponding from the codon of interest no matter what the SNP were C or T. However, phenylalanine, leucine and valine were produced at the same locus when the second SNP was T, C and G, respectively. Glutamine or arginine were produced when the fourth SNP was A or G, respectively. Also, serine was produced when the fifth SNP was C