DETERMINATION OF SUBCLINICAL ATHEROSCLEROSIS IN OBSTRUCTIVE SLEEP APNEA SYNDROME PATIENTS WITHOUT TRADITIONAL RISK FACTORS FOR ATHEROSCLEROSIS

Karakas M. S., ALTEKİN R. E., OZBEK S. C., YANIKOGLU A., AKDEMIR B., ER A., ...More

NOBEL MEDICUS, vol.9, no.3, pp.27-34, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 3
  • Publication Date: 2013
  • Journal Name: NOBEL MEDICUS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.27-34
  • Keywords: Obstructive sleep apnea, pulse wave analiysis, carotid intima-media thickness, atherosclerosis, INTIMA-MEDIA THICKNESS, PULSE-WAVE VELOCITY, CARDIOVASCULAR-DISEASE, ARTERIAL STIFFNESS, HYPERTENSIVE PATIENTS, AORTIC STIFFNESS, PRESSURE, ASSOCIATION, INFLAMMATION, INDICATOR
  • Akdeniz University Affiliated: Yes

Abstract

Objective: Obstructive sleep apnea-hypopnea syndrome (OSAS) is associated with high cardiovascular morbidity and mortality. Recent studies have suggested a pathophysiological link between OSAS and atherosclerosis; for which carotid intirna-media thickness (CIMT) and pulse wave velocity (PWV) has been considered as an early marker. The aim of this study was to assess the presence of early signs of atherosclerosis and cardiovascular effects of OSAS depending on its severity, in patients without clinically diagnosed cardiovascular disease and any coincident risk factors for atherosclerosis.